n mammals, including humans.

It has a number of effects, including:  Reproductive health: KP-10 stimulates the release of gonadotropins in men and women during the preovulatory phase of the menstrual cycle. It may have potential to treat reproductive disorders.  Bone health: KP-10 may play a role in bone protection by binding to Gpr54 in osteoclasts, which can negatively modulate osteoclast activities.  Heart health: KP-10 can increase the collagen content in human cardiac fibroblasts. However, it can also cause some degree of fibrosis in heart cells.  Vasoconstriction: KP-10 is a potent vasoconstrictor.  Angiogenesis: KP-10 inhibits angiogenesis.  Metastasis: KP-10 can inhibit metastasis and invasion in mouse melanomas.  Sexual arousal: KP-10 may help release the brake on sexual arousal by suppressing areas related to overthinking.

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