About MT1:

MT1  is melatonin receptors that  involved in a number of functions, including sleep regulation, mood disorders, and learning and memory

Functions：

Sleep regulation: MT1 receptors regulate non-rapid eye movement (NREM) sleep, while MT1 receptors increase rapid eye movement (REM) sleep；

Circadian rhythm: Melatonin controls the activity of the suprachiasmatic nucleus (SCN), the master circadian clock, via MT1 receptors. 

Mood disorders: MT1 receptors could be a target for new antidepressants；

Learning and memory: Melatonin receptors may play a role in learning and memory. 

Other functions: Melatonin receptors may also be involved in reproductive cycles, vasodilation, and systemic immunity.

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